- Lymphocytic Interstitial Pneumonitis (LIP) is a lymphoproliferative lung disorder.
- Pathologically there is diffuse infiltration of lymphocytes, plasma cells & immunoblasts along lymphatics & in alveolar septae.
- Diagnosis - open lung biopsy, with above histological features & infection excluded.
LIP Clinical Features:
- Uncommon.
- No obvious cause apparent.
- Presents with cough, dyspnoea & fever.
- Tends to occur earlier rather than later in the course of HIV infection.
LIP Radiological Examination:
Chest Xray:
- May be normal.
- Typically reveals reticular or nodular infiltrates.
- Infiltrates predominantly basilar in location.
CT Chest:
- Peribronchovascular nodules (2-4 mm in diameter).
- Ground glass opacities may be present.
LIP Prognosis:
- Varies from benign course (with spontaneous resolution or stabilisation) to respiratory failure.
Tags: HIV infection - LIP - Lymphocytic Interstitial Pneumonitis - Open Lung Biopsy
Posted by Medicalchemy
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Medicalchemy Group: History of Medicine - Images - Mnemonics - Syndromes - Anaesthesiology - Anatomy - Anthropology - Biochemistry - Cardiology - Dentistry - Dermatology - Drugs -Emergency Medicine - Endocrinology - Family Medicine - Gastroenterology - Genetics - Geriatrics - Gynecology - Haematology - Health Informatics - Hepatology - Immunology - Infection -Intensive Care - Metabolic Medicine - Microbiology - Nephrology - Neuroscience - Nuclear Medicine - Nutrition - Obstetrics - Occupational Health - Oncology - Ophthalmology -Orthopaedics - Otolaryngology - Palliative Care - Parasitology - Pathology - Pharmacology - Physiology - Psychiatry - Public Health - Radiology - Respiratory -Rehabilitation - Sports Medicine - Surgery - Toxicology - Tropical Medicine - Urology - Vascular - Virology.
