- Persistence of hyper-reactive airways following acute exposure to a respiratory irritant.
- Typically follows a work-related spill or accident.
- The exposure is usually single & intense.
- Can be thought of as an irritant induced asthma.
RADS Clinical Features:
- Symptoms of airways disease - dyspnoea, wheeze, cough.
- Occurring in patient with no previous history of respiratory disease.
- Symptoms beginning within 24 hours of exposure .
- No latent period of prior 'sensitization'.
- Re-exposure to a low dose of the irritant will typically not trigger asthma.
- In work-related cases, the patient may continue to work in the same building once measures have put in place to avoid exposure.
- Bronchial hyper-reactivity can demonstrated, ie methacholine challenge test.
- Pulmonary function tests may be normal or obstructive.
- The features noted may persist for months to years.
Irritant Agents (Examples):
- Acids
- Ammonia
- Chlorine
- Cleaning agents
- Smoke
Tags: Acids - Ammonia - Asthma - Chlorine - Cleaning Agents - Methacholine Challenge Test - RADS - Reactive Airways Dysfunction Syndrome - Smoke
Posted by Medicalchemy
Medicalchemy Group: History of Medicine - Images - Mnemonics - Syndromes - Acute Medicine - Anaesthesiology - Anatomy - Anthropology - Biochemistry - Cardiology - Dentistry - Dermatology - Drug ADR - Drugs - Embryology - Emergency Medicine - Endocrinology - Epidemiology - Family Medicine - Forensic Medicine - Gastroenterology - Genes - Genetics - Geriatrics - Gynecology - Haematology - Health Informatics - Hepatology - Immunology - Infection - Intensive Care - Medical Dictionary - Medical Education - Medical Statistics - Metabolic Medicine - Microbiology - Nephrology - Neuroanatomy - Neuroscience - Nuclear Medicine - Nutrition - Obstetrics - Occupational Health - Oncology - Ophthalmology - Orthopaedics - Otolaryngology - Paediatrics - Palliative Care - Parasitology - Pathology - Pharmacology - Physiology - Proteomics - Psychiatry - Public Health - Radiology - Respiratory - Rehabilitation - Rheumatology - Sports Medicine - Surgery - Toxicology - Tropical Medicine - Urology - Vascular - Virology.
Posted by Medicalchemy
Medicalchemy Group: History of Medicine - Images - Mnemonics - Syndromes - Acute Medicine - Anaesthesiology - Anatomy - Anthropology - Biochemistry - Cardiology - Dentistry - Dermatology - Drug ADR - Drugs - Embryology - Emergency Medicine - Endocrinology - Epidemiology - Family Medicine - Forensic Medicine - Gastroenterology - Genes - Genetics - Geriatrics - Gynecology - Haematology - Health Informatics - Hepatology - Immunology - Infection - Intensive Care - Medical Dictionary - Medical Education - Medical Statistics - Metabolic Medicine - Microbiology - Nephrology - Neuroanatomy - Neuroscience - Nuclear Medicine - Nutrition - Obstetrics - Occupational Health - Oncology - Ophthalmology - Orthopaedics - Otolaryngology - Paediatrics - Palliative Care - Parasitology - Pathology - Pharmacology - Physiology - Proteomics - Psychiatry - Public Health - Radiology - Respiratory - Rehabilitation - Rheumatology - Sports Medicine - Surgery - Toxicology - Tropical Medicine - Urology - Vascular - Virology.
