Drug-Induced Pulmonary Eosinophilia

Drug-Induced Pulmonary Eosinophilia:

• Drug associated transient pulmonary infiltrates, with an elevated eosinophil count.
• Clinical spectrum is variable.

Clinical Spectrum:

• Acute picture - simulating hypersensitivity pneumonitis - ie cocaine.
• Insidious onset picture - chronic symptoms & dyspnoea - ie nitrofurantoin.
• Loeffler-like picture - ie penicillin.
• Eosinophilic vasculitis picture - ie zafirlukast.

Drug Causes (Antibiotics):

• Ampicillin
• Minocycline
• Nitrofurantoin
• Penicillin
• Pentamidine (aerosolized)
• Sulfonamide

Drugs Causes (Other):

• Chlorpropamide
• Crack Cocaine
• L-tryptophan
• NSAIDs
• Paracetamol (Acetaminophen)
• Ranitidine
• Zafirlukast

Tags: Antibiotics - Cocaine - Drug-Induced Pulmonary Eosinophilia - Eosinophilic vasculitis - Nitrofurantoin - Pneumonitis - Pulmonary Eosinophilia - Pulmonary Infiltrate
Posted by Medicalchemy
Medicalchemy Group: History of Medicine - Images - Mnemonics - Syndromes - Acute Medicine - Anaesthesiology - Anatomy - Anthropology - Biochemistry - Cardiology - Dentistry - Dermatology - Drug ADR - Drugs - Embryology - Emergency Medicine - Endocrinology - Epidemiology - Family Medicine - Forensic Medicine - Gastroenterology - Genes - Genetics - Geriatrics - Gynecology - Haematology - Health Informatics - Hepatology - Immunology - Infection - Intensive Care - Medical Dictionary - Medical Education - Medical Statistics - Metabolic Medicine - Microbiology - Nephrology - Neuroanatomy - Neuroscience - Nuclear Medicine - Nutrition - Obstetrics - Occupational Health - Oncology - Ophthalmology - Orthopaedics - Otolaryngology - Paediatrics - Palliative Care - Parasitology - Pathology - Pharmacology - Physiology - Proteomics - Psychiatry - Public Health - Radiology - Respiratory - Rehabilitation - Rheumatology - Sports Medicine - Surgery - Toxicology - Tropical Medicine - Urology - Vascular - Virology.

Recurrent Pulmonary Infiltrates - Same Area Of Lung

Aetiology:

Bronchiectasis - Congenital or acquired

Bronchogenic cyst - recurrent infections

Broncho-oesophageal fistula - ie neoplastic

Bronchopulmonary sequestration - recurrent infections

Local bronchial narrowing:

* Intraluminal - broncholith, foreign body

* Endobronchial - neoplasm

* Peribronchial - lymph nodes, mediastinal mass

Tags: Bronchiectasis - Bronchogenic Cyst - Broncho-oesophageal Fistula - Bronchopulmonary Sequestration - Infection - Mediastrinal Mass - Neoplasm - Pulmonary Infiltrate
Posted by Medicalchemy
Medicalchemy Group: History of Medicine - Images - Mnemonics - Syndromes - Acute Medicine - Anaesthesiology - Anatomy - Anthropology - Biochemistry - Cardiology - Dentistry - Dermatology - Drug ADR - Drugs - Embryology - Emergency Medicine - Endocrinology - Family Medicine - Forensic Medicine - Gastroenterology - Genes - Genetics - Geriatrics - Gynecology - Haematology - Health Informatics - Hepatology - Immunology - Infection - Intensive Care - Medical Education - Metabolic Medicine - Microbiology - Nephrology - Neuroanatomy -Neuroscience - Nuclear Medicine - Nutrition - Obstetrics - Occupational Health - Oncology - Ophthalmology - Orthopaedics - Otolaryngology - Paediatrics - Palliative Care - Parasitology - Pathology - Pharmacology - Physiology - Proteomics - Psychiatry - Public Health - Radiology - Respiratory - Rehabilitation - Rheumatology - Sports Medicine - Surgery - Toxicology - Tropical Medicine - Urology - Vascular - Virology.

Upper Lobe Infiltrations or Fibrosis on Chest Xray

Aetiological Factors:

• Allergic alveolitis
• Ankylosing spondylitis
• Eosiniphilic granuloma
• Histoplasmosis
• Radiation pneumonitis
• Rheumatoid arthritis
• Rhodococcus equi
• Sarcoidosis
• Silicosis progressive massive fibrosis
• Sporotrichosis
• Talcosis
• Tuberculosis

Tags: Chest Xray - Pulmonary infiltrate - Pulmonary fibrosis - Tuberculosis - Upper Lobe

Posted by Medicalchemy
Medicalchemy Group: History of Medicine - Images - Mnemonics - Anaesthesiology - Anatomy - Biochemistry - Cardiology - Dermatology - Drugs - Endocrinology - Gastroenterology -Genetics - Geriatrics - Gynecology - Haematology - Immunology - Infection - Metabolic Medicine - Microbiology - Nephrology - Neuroscience - Nutrition - Obstetrics - Oncology - Ophthalmology - Orthopaedics - Otolaryngology - Palliative Care - Pathology - Pharmacology - Physiology - Psychiatry - Public Health - Respiratory - Surgery - Toxicology - Tropical Medicine - Urology - Vascular.